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Prostate Problem Guide

The Use Of Medicine In BPH Treatment

There are a number of ways of treating BPH (benign prostatic hyperplasia or an enlarged prostate) of which medical treatments, or the use of drugs, is the commonest form of treatment following watchful waiting.

(Watchful waiting applies in cases where symptoms are mild or where the patient is not particularly troubled by his symptoms and involves simply checking on the patient once or twice a year to ensure that he is not developing complications as a result of his BPH. This can be a useful option for some patients as it avoids the risks associated with other forms of BPH treatment and, on occasions, the symptoms will actually lessen over time.)

One commonly used group of drugs in BPH treatment are alpha-blockers which were originally designed for the treatment of high blood pressure. Alpha-blockers act to relax the muscles of the prostate gland, as well as the neck of the bladder, and so reduce pressure on the urethra and improve the flow of urine.

Although alpha-blockers relieve BPH symptoms they do not reduce the size of the prostate and so the symptoms are likely to return if treatment is stopped. Alpha-blockers will usually produce a moderate reduction in symptoms and common side effects include dizziness, headaches, a stuffy nose and stomach and intestinal problems. These problems appear in about 12% to 15% of patients.

Some terms your doctor might use when talking about prostate cancer:

AZOTEMIA: elevation in blood nitrogen level due to dehydration or kidney dysfunction; in laboratory tests this manifests as elevation in BUN and/or creatinine.

GENITOURINARY SYSTEM (GU SYSTEM): In the male, pertaining to the organs comprising the genital and urinary system. This includes the testicles, penis, seminal vesicles, urethra, bladder, ureters and kidneys.

LATENT: insignificant or irrelevant; for example, latent prostate cancer (also known as incidental prostate cancer) is a form of prostate cancer which is of no clinical significance to the patient in whom it is discovered.

SECONDARY TO: derived from or consequent to a primary event or thing.

Another frequently prescribed group of drugs are 5-alpha reductase inhibitors. This particular group of drugs acts to lower the level of the main male hormone found in the prostate gland and thus marginally reduces the size of the enlarged prostate. It is however a very slow acting drug and patients will normally need to take the drug for 6 to 12 months before any effects are evident.

5-alpha reductase inhibitors usually produce less of a reduction in symptoms than alpha blockers but can be particular useful in cases where the prostate is considerably enlarged and patients are at risk of developing acute retention – an inability to urinate. Common side effects resulting from the reduction of the male hormone include erection problems, a decrease in sexual desire and a reduction in the amount of semen produced. These problems are seen in about 5% to 8% of patients.

In cases where the prostate is particularly enlarged and patients are finding that they are especially troubled by their symptoms, the doctor may recommend a combination of both alpha-blockers and 5-alpha reductase inhibitors.

In addition to prescription drugs patients may also wish to consider the use of herbal remedies. A number of such over-the-counter remedies are available but, at present, their effectiveness and safety have not been proved and none are approved for use by the Food and Drug Administration (FDA). In addition, the use of some of the herbal remedies available can lead to distortions in the results of diagnostic tests and also interfere with the actions of prescription drugs. As a result, you should consult your doctor before using any form of herbal remedy.

Further information on bph:

Beyond the Abstract - Benign prostatic hyperplasia: Symptoms, symptom scores ... - UroToday


Beyond the Abstract - Benign prostatic hyperplasia: Symptoms, symptom scores ...
UroToday
BERKELEY, CA (UroToday.com) - Our chapter on BPH in the recent Urologic Clinics of North America focuses on improved methods for defining the etiology of ...

Laser prostate treatment - WVLT


Laser prostate treatment
WVLT
By the time they hit their 60th birthdays, half of all men will have a condition called benign prostatic hyperplasia, or bph. It's a natural enlargement of ...

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BPH Again Linked to Inflammation - Renal and Urology News


BPH Again Linked to Inflammation
Renal and Urology News
Systemic inflammation or low levels of soluble receptors that bind inflammatory cytokines increase the risk of benign prostatic hyperplasia (BPH), ...

Generic Drug for Enlarged Prostate Approved - WebMD


Rediff

Generic Drug for Enlarged Prostate Approved
WebMD
Enlargement of the prostate gland, a condition known as benign prostatic hyperplasia (BPH), is common among men as they age. More than half of men 60 and ...
FDA Okays Generic of BPH DrugMedPage Today
Generic Flomax Approved for Enlarged ProstateBusinessWeek
Impax Laboratories wins FDA approval for BPH drugTrading Markets (press release)
About - News & Issues (blog) -Bizjournals.com -PharmExec.com
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